secobarbital will lessen the extent or effect of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Solid or average CYP3A4 inducers may well boost price of diazepam elimination; thus, efficacy of diazepam might be lessened.secobarbital will minimize the level or effect of atogepant by influenc